InChIKey	RPTUSVTUFVMDQK-UHFFFAOYSA-N
Canonical SMILES	NNc1nncc2ccccc12
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	6.21
Source	ChEMBL;BindingDB

DrugBank ID	DB01275
Drug Name	Hydralazine
CAS Number	86-54-4
Groups	approved investigational
ATC Codes	C02DB02 C02LG02
Description	Originally developed in the 1950s as a malaria treatment, hydralazine showed antihypertensive ability and was soon repurposed.[A186841] Hydralazine is a hydrazine derivative vasodilator used alone or as adjunct therapy in the treatment of hypertension and only as adjunct therapy in the treatment of ...

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Categories: Antihypertensive Agents Antihypertensive Agents Indicated for Hypertension Arteriolar Smooth Muscle, Agents Acting On Arteriolar Vasodilation Arteriolar Vasodilator Cardiovascular Agents Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inhibitors Direct Vasodilators Drugs that are Mainly Renally Excreted Hydrazinophthalazine Derivatives Hydrazinophthalazine Derivatives and Diuretics Hypotensive Agents Phthalazines Pyridazines Vasodilating Agents

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Cross-references: BindingDB: 81461 ChEBI: 5775 CHEMBL276832 ChemSpider: 3511 Drugs Product Database (DPD): 6436 C07040 D08044 PDB: HLZ PharmGKB: PA449894 PubChem:3637 PubChem:46507533 RxCUI: 5470 Therapeutic Targets Database: DAP000728 Wikipedia: Hydralazine ZINC: ZINC000012360535