Molecule Details
InChIKeyROKOFZNQCIIJMI-UHFFFAOYSA-N
Compound NameSB-216995
Canonical SMILESFc1ccc(-c2ncn(CC3CC3)c2-c2ccncc2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)4
Pfam Stratification Homologous
Avg pChEMBL7.21
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB08522
Drug Name4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan
Cross-references: BindingDB: 15237 CHEMBL96741 ChemSpider: 4984 PDB: SB6 PubChem:5171 PubChem:99444993 ZINC: ZINC000002047872
Target Activities (4)
Target Gene Organism Category Pfam pChEMBL Type Source
O15264 MAPK13 Homo sapiens Human PF00069 7.3 IC50 ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 7.3 IC50 ChEMBL
Q15759 MAPK11 Homo sapiens Human PF00069 7.3 IC50 ChEMBL
Q16539 MAPK14 Homo sapiens Human PF00069 6.8 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q16539 MAPK14 Mitogen-activated protein kinase 14 inhibitor targets