Molecule Details
| InChIKey | ROGUAPYLUCHQGK-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(4-tert-Butylphenyl)-4-(3-chloropyridin-2-yl)tetrahydropyrazine-1(2H)-carboxamide |
| Canonical SMILES | CC(C)(C)c1ccc(NC(=O)N2CCN(c3ncccc3Cl)CC2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.79 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q8NER1 | TRPV1 | Homo sapiens | Human | PF00023 PF12796 PF00520 | 8.2 | IC50 | ChEMBL;BindingDB |
| Q7Z2W7 | TRPM8 | Homo sapiens | Human | PF00520 PF18139 PF25508 | 6.2 | IC50 | ChEMBL;BindingDB |
| Q12809 | KCNH2 | Homo sapiens | Human | PF00027 PF00520 PF13426 | 6.0 | IC50 | ChEMBL;BindingDB |