Molecule Details
InChIKeyRMZISWVBRKVMOJ-UHFFFAOYSA-N
Canonical SMILESC=CC(=O)Nc1cc2c(cc1OCCNC(=O)CN(C)C)NCN=C2Nc1ccc(Br)cc1F
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.75
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 8.5 IC50 ChEMBL;BindingDB
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.0 IC50 ChEMBL;BindingDB