(2S,3R)-N'-[(2S)-1-anilino-3,3-dimethyl-1-oxobutan-2-yl]-N-hydroxy-2-methyl-3-(2-methylpropyl)-2-prop-2-enylbutanediamide

InChIKey	`RMDCZACTUKUROI-GLDPYIMESA-N`
Compound Name	(2S,3R)-N'-[(2S)-1-anilino-3,3-dimethyl-1-oxobutan-2-yl]-N-hydroxy-2-methyl-3-(2-methylpropyl)-2-prop-2-enylbutanediamide
Canonical SMILES	`C=CC[C@](C)(C(=O)NO)[C@@H](CC(C)C)C(=O)N[C@H](C(=O)Nc1ccccc1)C(C)(C)C`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	7.61
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	8.2	pIC50	TTD_MultiTarget
Q9ULZ9	MMP17	Homo sapiens	Human	PF00045 PF00413 PF01471	7.8	pIC50	TTD_MultiTarget
P03956	MMP1	Homo sapiens	Human	PF00045 PF00413 PF01471	7.3	IC50	ChEMBL;BindingDB
P08254	MMP3	Homo sapiens	Human	PF00045 PF00413 PF01471	7.0	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	7.8	pIC50	TTD_MultiTarget