Molecule Details
InChIKeyRLRQXKXWZNPYRB-UHFFFAOYSA-N
Compound NameEciruciclib
Canonical SMILESCCN1CCN(Cc2ccc(Nc3ncc(F)c(-c4ccc5nn(C)c(C(C)C)c5c4)n3)nc2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.91
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB21597
Drug NameEciruciclib
CAS Number1868086-40-1
Groups experimental
ATC Codes nan
DescriptionEciruciclib is a small molecule drug. The usage of the INN stem '-ciclib' in the name indicates that Eciruciclib is a cyclin dependant kinase inhibitor. Eciruciclib has a monoisotopic molecular weight of 488.28 Da.

Cross-references: BindingDB: 50644903 CHEMBL5095060
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P11802 CDK4 Homo sapiens Human PF00069 9.1 IC50 ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 8.9 IC50 ChEMBL
Q00534 CDK6 Homo sapiens Human PF00069 8.7 IC50 ChEMBL