(4R)-N-[3-[4-cyano-4-(2,4-difluorophenyl)piperidin-1-yl]propyl]-4-(3,4-difluorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyridine-5-carboxamide

InChIKey	`RLMGUPUESXPDFJ-HXUWFJFHSA-N`
Compound Name	(4R)-N-[3-[4-cyano-4-(2,4-difluorophenyl)piperidin-1-yl]propyl]-4-(3,4-difluorophenyl)-6-methyl-2-oxo-3,4-dihydro-1H-pyridine-5-carboxamide
Canonical SMILES	`CC1=C(C(=O)NCCCN2CCC(C#N)(c3ccc(F)cc3F)CC2)[C@@H](c2ccc(F)c(F)c2)CC(=O)N1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Homologous
Avg pChEMBL	6.91
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35348	ADRA1A	Homo sapiens	Human	PF00001	9.0	pIC50	TTD_MultiTarget
P35367	HRH1	Homo sapiens	Human	PF00001	7.0	Ki	ChEMBL;BindingDB
P18089	ADRA2B	Homo sapiens	Human	PF00001	6.3	Ki	ChEMBL;BindingDB
P25100	ADRA1D	Homo sapiens	Human	PF00001	6.2	Ki	ChEMBL;BindingDB
P35368	ADRA1B	Homo sapiens	Human	PF00001	6.1	Ki	ChEMBL;BindingDB