3-{4-Amino-7-[1-hydroxymethyl-2-(4-methoxy-phenyl)-ethyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-phenol

InChIKey	`RLICCWOKSVSSOF-UHFFFAOYSA-N`
Compound Name	3-{4-Amino-7-[1-hydroxymethyl-2-(4-methoxy-phenyl)-ethyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-phenol
Canonical SMILES	`COc1ccc(CC(CO)n2cc(-c3cccc(O)c3)c3c(N)ncnc32)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	5
Pfam Stratification	Cross-Family
Avg pChEMBL	6.47
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00519	ABL1	Homo sapiens	Human	PF08919 PF07714 PF00017 PF00018	6.5	IC50	ChEMBL;BindingDB
P18505	GABRB1	Homo sapiens	Human	PF02931 PF02932	6.5	pIC50	TTD_MultiTarget
P42684	ABL2	Homo sapiens	Human	PF08919 PF07714 PF00017 PF00018	6.5	IC50	ChEMBL
P00533	EGFR	Homo sapiens	Human	PF00757 PF14843 PF07714 PF01030 PF21314	Clinical	TTD_MultiTarget	TTD_MultiTarget
P12931	SRC	Homo sapiens	Human	PF07714 PF00017 PF00018	Clinical	TTD_MultiTarget	TTD_MultiTarget