Molecule Details
InChIKeyRKWOVOVDWBRGQO-XMMPIXPASA-N
Compound Name(7~{R})-2-[[2-ethoxy-4-(1-methylpiperidin-4-yl)phenyl]amino]-7-ethyl-5-methyl-8-[(4-methylthiophen-2-yl)methyl]-7~{H}-pteridin-6-one
Canonical SMILESCCOc1cc(C2CCN(C)CC2)ccc1Nc1ncc2c(n1)N(Cc1cc(C)cs1)[C@H](CC)C(=O)N2C
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)5
Pfam Stratification Cross-Family
Avg pChEMBL7.3
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (5)
Target Gene Organism Category Pfam pChEMBL Type Source
P53350 PLK1 Homo sapiens Human PF00069 PF00659 8.0 Kd ChEMBL;BindingDB
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 7.6 IC50 ChEMBL;BindingDB
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 7.4 Kd ChEMBL;BindingDB
Q9H4B4 PLK3 Homo sapiens Human PF00069 PF00659 6.8 Kd ChEMBL;BindingDB
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.7 Kd ChEMBL;BindingDB