Molecule Details
InChIKeyRKBYYWVZFBATHQ-UHFFFAOYSA-N
Compound Name1-[4-[4-Methyl-5-(3,4,5-trimethoxyphenyl)pyridin-3-yl]phenyl]piperazine
Canonical SMILESCOc1cc(-c2cncc(-c3ccc(N4CCNCC4)cc3)c2C)cc(OC)c1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL6.87
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 7.9 IC50 ChEMBL;BindingDB
P37023 ACVRL1 Homo sapiens Human PF07714 PF08515 7.8 IC50 ChEMBL;BindingDB
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 7.4 IC50 ChEMBL;BindingDB
O00238 BMPR1B Homo sapiens Human PF01064 PF07714 PF08515 7.2 IC50 ChEMBL;BindingDB
Q9UKE5 TNIK Homo sapiens Human PF00780 PF00069 7.0 IC50 ChEMBL;BindingDB
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.5 IC50 ChEMBL;BindingDB
Q13882 PTK6 Homo sapiens Human PF07714 PF00017 PF00018 6.5 IC50 ChEMBL;BindingDB
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.5 IC50 ChEMBL;BindingDB
Q9H0K1 SIK2 Homo sapiens Human PF00069 PF23312 6.5 IC50 ChEMBL;BindingDB
Q9NYL2 MAP3K20 Homo sapiens Human PF07714 PF07647 6.5 IC50 ChEMBL;BindingDB
Q9UBE8 NLK Homo sapiens Human PF00069 6.5 IC50 ChEMBL;BindingDB
P36894 BMPR1A Homo sapiens Human PF01064 PF07714 PF08515 6.4 IC50 ChEMBL;BindingDB