Molecule Details
InChIKeyRJZUURDJHFCQRS-UHFFFAOYSA-N
Canonical SMILESCCNc1nc(-c2cccc(-c3cccc(-c4cnc(CN5CC6(C5)CN(C(C)=O)C6)c(NCC)n4)c3Cl)c2Cl)cnc1CN1CC2(C1)CN(C(C)=O)C2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL9.78
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q15116 PDCD1 Homo sapiens Human PF07686 9.8 IC50 ChEMBL;BindingDB
Q9NZQ7 CD274 Homo sapiens Human PF08205 PF07686 9.8 IC50 ChEMBL