Molecule Details
| InChIKey | RJSXJUGBWBWHSB-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-[3-(2-bicyclo[2.2.1]heptanyloxy)-4-methoxyphenyl]-3H-benzimidazole-5-carboxylic acid |
| Canonical SMILES | COc1ccc(-c2nc3cc(C(=O)O)ccc3[nH]2)cc1OC1CC2CCC1C2 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.99 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P27815 | PDE4A | Homo sapiens | Human | PF18100 PF00233 | 7.0 | IC50 | ChEMBL |
| Q07343 | PDE4B | Homo sapiens | Human | PF18100 PF00233 | 7.0 | IC50 | ChEMBL |
| Q08493 | PDE4C | Homo sapiens | Human | PF18100 PF00233 | 7.0 | IC50 | ChEMBL |
| Q08499 | PDE4D | Homo sapiens | Human | PF18100 PF00233 | 7.0 | IC50 | ChEMBL |