Molecule Details
InChIKeyRIWTUJFFSTVYPW-UHFFFAOYSA-N
Compound Name2-Fluoro-6-methoxy-4-[4-methyl-5-[4-(4-propan-2-ylpiperazin-1-yl)phenyl]-3-pyridinyl]benzamide
Canonical SMILESCOc1cc(-c2cncc(-c3ccc(N4CCN(C(C)C)CC4)cc3)c2C)cc(F)c1C(N)=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.52
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 8.2 IC50 ChEMBL;BindingDB
P36896 ACVR1B Homo sapiens Human PF01064 PF00069 PF08515 7.9 IC50 ChEMBL
P37023 ACVRL1 Homo sapiens Human PF07714 PF08515 7.8 IC50 ChEMBL
Q9UKE5 TNIK Homo sapiens Human PF00780 PF00069 7.4 IC50 ChEMBL
O00238 BMPR1B Homo sapiens Human PF01064 PF07714 PF08515 7.1 IC50 ChEMBL
P36894 BMPR1A Homo sapiens Human PF01064 PF07714 PF08515 6.8 IC50 ChEMBL