Molecule Details
InChIKeyRHLJLALHBZGAFM-UHFFFAOYSA-N
Compound NameBunazosin
Canonical SMILESCCCC(=O)N1CCCN(c2nc(N)c3cc(OC)c(OC)cc3n2)CC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.91
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12230
Drug NameBunazosin
CAS Number80755-51-7
Groups investigational
ATC Codes nan
DescriptionBunazosin has been used in trials studying the treatment of High Blood Pressure.

Categories: Adrenergic Agents Adrenergic Antagonists Adrenergic alpha-1 Receptor Antagonists Adrenergic alpha-Antagonists Heterocyclic Compounds, Fused-Ring Neurotransmitter Agents Peripheral alpha-1 blockers
Cross-references: BindingDB: 50088386 ChEBI: 135576 CHEMBL188185 ChemSpider: 2378 PubChem:2472 PubChem:347828509 RxCUI: 19850 Wikipedia: Bunazosin ZINC: ZINC000000601249
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P25100 ADRA1D Homo sapiens Human PF00001 8.9 IC50 ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 8.9 IC50 ChEMBL
P35368 ADRA1B Homo sapiens Human PF00001 8.9 IC50 ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P25100 ADRA1D Alpha-1D adrenergic receptor modulator targets