Molecule Details
InChIKeyRHFIAUKMKYHHFA-UHFFFAOYSA-N
Compound NameGne-3511
Canonical SMILESN#Cc1ccnc(Nc2cc(C3CCN(C4COC4)CC3)cc(N3CCC(F)(F)C3)n2)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)9
Pfam Stratification Cross-Family
Avg pChEMBL7.12
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (9)
Target Gene Organism Category Pfam pChEMBL Type Source
P80370 DLK1 Homo sapiens Human PF00008 9.0 Kd BindingDB
O43283 MAP3K13 Homo sapiens Human PF07714 8.5 IC50 ChEMBL;BindingDB
Q12852 MAP3K12 Homo sapiens Human PF07714 7.5 IC50 ChEMBL;BindingDB
P80192 MAP3K9 Homo sapiens Human PF07714 PF14604 7.2 IC50 ChEMBL;BindingDB
P45983 MAPK8 Homo sapiens Human PF00069 6.9 IC50 ChEMBL;BindingDB
P53779 MAPK10 Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB
P45984 MAPK9 Homo sapiens Human PF00069 6.3 IC50 ChEMBL;BindingDB
Q16584 MAP3K11 Homo sapiens Human PF07714 PF14604 6.2 IC50 ChEMBL;BindingDB
Q02779 MAP3K10 Homo sapiens Human PF07714 PF14604 6.1 IC50 ChEMBL;BindingDB