Molecule Details
InChIKeyRGVVHQNJKUNSFQ-WDZFZDKYSA-N
Compound Name4-(5-{[(5Z)-2-imino-4-oxo-1,3-thiazolidin-5-ylidene]methyl}furan-2-yl)-2-(trifluoromethyl)benzene-1-sulfonamide
Canonical SMILESN=C1NC(=O)/C(=C/c2ccc(-c3ccc(S(N)(=O)=O)c(C(F)(F)F)c3)o2)S1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.46
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB07538
Drug Name4-{5-[(Z)-(2-IMINO-4-OXO-1,3-THIAZOLIDIN-5-YLIDENE)METHYL]FURAN-2-YL}-2-(TRIFLUOROMETHYL)BENZENESULFONAMIDE
CAS Numbernan
Groups experimental
ATC Codes nan
Descriptionnan

Cross-references: BindingDB: 17149 CHEMBL233970 ChemSpider: 22376747 PDB: C94 PubChem:23647657 PubChem:99444009 ZINC: ZINC000014963245
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P49841 GSK3B Homo sapiens Human PF00069 8.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.2 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P20248 CCNA2 Cyclin-A2 binder targets
P24941 CDK2 Cyclin-dependent kinase 2 binder targets