1-(4-Chloropyrimido[4,5-b][1,4]benzoxazepin-8-yl)-3-[4-chloro-3-(trifluoromethyl)phenyl]urea

InChIKey	`RGGIEVPMRLEMRX-UHFFFAOYSA-N`
Compound Name	1-(4-Chloropyrimido[4,5-b][1,4]benzoxazepin-8-yl)-3-[4-chloro-3-(trifluoromethyl)phenyl]urea
Canonical SMILES	`O=C(Nc1ccc2c(c1)C=Nc1c(Cl)ncnc1O2)Nc1ccc(Cl)c(C(F)(F)F)c1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	6.35
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.3	IC50	ChEMBL;BindingDB
Q02161	RHD	Homo sapiens	Human	PF00909	6.3	pIC50	TTD_MultiTarget