Molecule Details
InChIKeyREGFWZVTTFGQOJ-UHFFFAOYSA-N
Canonical SMILESNC1=NCCS1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.22
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB02335
Drug Name2-Aminothiazoline
CAS Number1779-81-3
Groups experimental
ATC Codes nan
Descriptionnan
Categories: Sulfur Compounds
Cross-references: BindingDB: 50150920 ChEBI: 40889 CHEMBL362148 ChemSpider: 14923 PDB: ATQ PubChem:15689 PubChem:46506807 ZINC: ZINC000018354955
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P29475 NOS1 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 PF00595 6.4 Ki ChEMBL;BindingDB
P35228 NOS2 Homo sapiens Human PF00667 PF00258 PF00175 PF02898 6.0 IC50 ChEMBL;BindingDB
DrugBank Target Actions (3)
Target Gene Target Name Action Type
P29474 NOS3 Nitric oxide synthase 3 inhibitor targets
P29475 NOS1 Nitric oxide synthase 1 inhibitor targets
P35228 NOS2 Nitric oxide synthase, inducible inhibitor targets