Molecule Details
| InChIKey | RDWRDUFEWMSPGQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-(1-[1,1-di(pyridin-2-yl)ethyl]-6-{1-methyl-6-oxo-5-[(piperidin-4-yl)amino]-1,6-dihydropyridin-3-yl}-1H-indol-4-yl)ethanesulfonamide |
| Canonical SMILES | CCS(=O)(=O)Nc1cc(-c2cc(NC3CCNCC3)c(=O)n(C)c2)cc2c1ccn2C(C)(c1ccccn1)c1ccccn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.84 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q58F21 | BRDT | Homo sapiens | Human | PF17035 PF17105 PF00439 | 8.0 | Kd | ChEMBL |
| O60885 | BRD4 | Homo sapiens | Human | PF17035 PF17105 PF00439 | 8.0 | Kd | ChEMBL |
| Q15059 | BRD3 | Homo sapiens | Human | PF17035 PF00439 | 7.8 | Kd | ChEMBL |
| P25440 | BRD2 | Homo sapiens | Human | PF17035 PF00439 | 7.5 | Kd | ChEMBL |