N-(4-bromo-3-(1-methyl-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydro-1,5-naphthyridin-1(2H)-yl)acetamide

InChIKey	`RDFFZPKZBXFQEF-UHFFFAOYSA-N`
Compound Name	N-(4-bromo-3-(1-methyl-1H-1,2,4-triazol-3-yl)thiophen-2-yl)-2-(2-oxo-3,4-dihydro-1,5-naphthyridin-1(2H)-yl)acetamide
Canonical SMILES	`Cn1cnc(-c2c(Br)csc2NC(=O)CN2C(=O)CCc3ncccc32)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	8.47
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P45983	MAPK8	Homo sapiens	Human	PF00069	9.0	IC50	ChEMBL;BindingDB
P53779	MAPK10	Homo sapiens	Human	PF00069	8.5	IC50	ChEMBL;BindingDB
P45984	MAPK9	Homo sapiens	Human	PF00069	7.9	IC50	ChEMBL;BindingDB