Molecule Details
| InChIKey | RBMOLIOJAWRTIV-OAHLLOKOSA-N |
|---|---|
| Compound Name | 4-{[(1S)-1-(3-fluorophenyl)-2-(methylamino)ethyl]amino}quinazoline-8-carboxamide |
| Canonical SMILES | CNC[C@@H](Nc1ncnc2c(C(N)=O)cccc12)c1cccc(F)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.61 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P23443 | RPS6KB1 | Homo sapiens | Human | PF00069 PF00433 | 9.2 | IC50 | ChEMBL;BindingDB |
| P31749 | AKT1 | Homo sapiens | Human | PF00169 PF00069 PF00433 | 8.4 | IC50 | ChEMBL;BindingDB |
| Q96GD4 | AURKB | Homo sapiens | Human | PF00069 | 8.4 | IC50 | ChEMBL;BindingDB |
| Q9NQS7 | INCENP | Homo sapiens | Human | PF03941 PF12178 | 8.4 | IC50 | ChEMBL |