2-N-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]-8-N-(2-methylpropyl)pyrido[3,4-d]pyrimidine-2,8-diamine

InChIKey	`QZZFLPGPIFLIDL-UHFFFAOYSA-N`
Compound Name	2-N-[2-methoxy-4-(1-methylpyrazol-4-yl)phenyl]-8-N-(2-methylpropyl)pyrido[3,4-d]pyrimidine-2,8-diamine
Canonical SMILES	`COc1cc(-c2cnn(C)c2)ccc1Nc1ncc2ccnc(NCC(C)C)c2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.85
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P33981	TTK	Homo sapiens	Human	PF00069	8.1	IC50	ChEMBL;BindingDB
P20248	CCNA2	Homo sapiens	Human	PF02984 PF00134 PF16500	6.2	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.2	IC50	ChEMBL;BindingDB