Molecule Details
InChIKeyQZPFUALVXZAFDD-UHFFFAOYSA-N
Compound Name1-[4-(7-ethyl-5H-pyrrolo[2,3-b]pyrazin-6-yl)phenyl]ethanone
Canonical SMILESCCc1c(-c2ccc(C(C)=O)cc2)[nH]c2nccnc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.45
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 7.0 Ki ChEMBL
P49336 CDK8 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.6 Ki ChEMBL
P45983 MAPK8 Homo sapiens Human PF00069 6.5 Ki ChEMBL
O14965 AURKA Homo sapiens Human PF00069 6.4 Ki ChEMBL
P48729 CSNK1A1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 6.1 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 6.0 Ki ChEMBL