4-[(2-methyl-6-propan-2-ylthieno[2,3-d]pyrimidin-4-yl)amino]-N-[4-(morpholin-4-ylmethyl)phenyl]-1H-pyrazole-5-carboxamide

InChIKey	`QYUAZFYQXCJXEM-UHFFFAOYSA-N`
Compound Name	4-[(2-methyl-6-propan-2-ylthieno[2,3-d]pyrimidin-4-yl)amino]-N-[4-(morpholin-4-ylmethyl)phenyl]-1H-pyrazole-5-carboxamide
Canonical SMILES	`Cc1nc(Nc2c[nH]nc2C(=O)Nc2ccc(CN3CCOCC3)cc2)c2cc(C(C)C)sc2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	8.09
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	9.2	IC50	ChEMBL;BindingDB
P24941	CDK2	Homo sapiens	Human	PF00069	7.6	IC50	ChEMBL;BindingDB
Q00534	CDK6	Homo sapiens	Human	PF00069	7.5	IC50	ChEMBL;BindingDB