InChIKey	QYSPLQLAKJAUJT-UHFFFAOYSA-N
Compound Name	Piroxicam
Canonical SMILES	CN1C(C(=O)Nc2ccccn2)=C(O)c2ccccc2S1(=O)=O
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	6.45
Source	BindingDB

DrugBank ID	DB00554
Drug Name	Piroxicam
CAS Number	36322-90-4
Groups	approved investigational
ATC Codes	M01AC01 M02AA07 S01BC06
Description	A cyclooxygenase inhibiting, non-steroidal anti-inflammatory agent (NSAID) that is well established in treating rheumatoid arthritis and osteoarthritis and used for musculoskeletal disorders, dysmenorrhea, and postoperative pain. Its long half-life enables it to be administered once daily.

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Categories: Agents causing hyperkalemia Agents that produce hypertension Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Anti-Inflammatory Agents, Non-Steroidal (Non-Selective) Antiinflammatory Preparations, Non-Steroids for Topical Use Antiinflammatory and Antirheumatic Products Antiinflammatory and Antirheumatic Products, Non-Steroids Antirheumatic Agents Cyclooxygenase Inhibitors Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs causing inadvertant photosensitivity Drugs that are Mainly Renally Excreted Enzyme Inhibitors Musculo-Skeletal System Nephrotoxic agents Non COX-2 selective NSAIDS OAT1/SLC22A6 inhibitors OAT3/SLC22A8 Inhibitors Ophthalmologicals Organic Anion Transporting Polypeptide 2B1 Inhibitors Other Nonsteroidal Anti-inflammatory Agents Oxicams Peripheral Nervous System Agents Photosensitizing Agents Sensory Organs Sensory System Agents Sulfur Compounds Thiazines Topical Products for Joint and Muscular Pain

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Cross-references: BindingDB: 85245 ChEBI: 8249 CHEMBL527 ChemSpider: 10442653 Drugs Product Database (DPD): 1996 C01608 D00127 PharmGKB: PA450985 PubChem:54676228 PubChem:46505225 RxCUI: 8356 Therapeutic Targets Database: DAP000181 Wikipedia: Piroxicam ZINC: ZINC000051133897