Molecule Details
InChIKeyQYGMZFLXMWJYRJ-UHFFFAOYSA-N
Compound NameN-[1-butyl-5-[cyclohexanecarbonyl(methyl)amino]benzimidazol-2-yl]-3-cyanobenzamide
Canonical SMILESCCCCn1c(NC(=O)c2cccc(C#N)c2)nc2cc(N(C)C(=O)C3CCCCC3)ccc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL6.54
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
P51617 IRAK1 Homo sapiens Human PF00531 PF00069 7.8 Ki ChEMBL
Q9NWZ3 IRAK4 Homo sapiens Human PF07714 7.0 Ki ChEMBL
P48730 CSNK1D Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q08881 ITK Homo sapiens Human PF00779 PF00169 PF07714 PF00017 PF00018 6.7 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.7 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.4 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.1 Ki ChEMBL
Q9Y6M4 CSNK1G3 Homo sapiens Human PF12605 PF00069 6.1 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.0 Ki ChEMBL