2-[5-[3-[(4-Methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile

InChIKey	`QYAPJFAWWAJNJA-UHFFFAOYSA-N`
Compound Name	2-[5-[3-[(4-Methyl-5-pyrazin-2-yl-1,2,4-triazol-3-yl)sulfanyl]propyl]-2,3,3a,4,6,6a-hexahydropyrrolo[2,3-c]pyrrol-1-yl]benzonitrile
Canonical SMILES	`Cn1c(SCCCN2CC3CCN(c4ccccc4C#N)C3C2)nnc1-c1cnccn1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.16
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P35462	DRD3	Homo sapiens	Human	PF00001	8.2	Ki	ChEMBL;BindingDB
Q12809	KCNH2	Homo sapiens	Human	PF00027 PF00520 PF13426	6.7	IC50	ChEMBL;BindingDB
P14416	DRD2	Homo sapiens	Human	PF00001	6.6	Ki	ChEMBL;BindingDB