Molecule Details
InChIKeyQXWUFUZJYLBZQF-LBPRGKRZSA-N
Compound NameN-{4-[3-(2-amino-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidin-6-yl)propyl]thiophene-2-carbonyl}-L-glutamic acid
Canonical SMILESNc1nc2sc(CCCc3csc(C(=O)N[C@@H](CCC(=O)O)C(=O)O)c3)cc2c(=O)[nH]1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Cross-Family
Avg pChEMBL8.65
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P14207 FOLR2 Homo sapiens Human PF03024 9.6 IC50 ChEMBL;BindingDB
P15328 FOLR1 Homo sapiens Human PF03024 9.4 IC50 ChEMBL;BindingDB
Q96NT5 SLC46A1 Homo sapiens Human PF07690 7.0 IC50 ChEMBL;BindingDB