Molecule Details
InChIKeyQXPNJMHRUZCEAP-UXBSLASESA-N
Compound NameDesepoxyhypothemycin
Canonical SMILESCOc1cc(O)c2c(c1)CCC[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL7.14
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 9.0 IC50 ChEMBL
P16234 PDGFRA Homo sapiens Human PF07679 PF25305 PF07714 8.6 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 8.4 IC50 ChEMBL
P36507 MAP2K2 Homo sapiens Human PF00069 8.0 IC50 ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 8.0 IC50 ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 7.2 IC50 ChEMBL
P37023 ACVRL1 Homo sapiens Human PF07714 PF08515 6.9 IC50 ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.5 IC50 ChEMBL
Q9BUB5 MKNK1 Homo sapiens Human PF00069 6.5 IC50 ChEMBL
P52564 MAP2K6 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
Q8IW41 MAPKAPK5 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
P06239 LCK Homo sapiens Human PF07714 PF00017 PF00018 6.1 IC50 ChEMBL
Q9UM73 ALK Homo sapiens Human PF12810 PF00629 PF07714 6.1 IC50 ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 6.0 IC50 ChEMBL