8-N-(2-fluorophenyl)-2-N-(4-methoxyphenyl)-9-(oxan-4-yl)purine-2,8-diamine

InChIKey	`QXNPNLLIZGVUPQ-UHFFFAOYSA-N`
Compound Name	8-N-(2-fluorophenyl)-2-N-(4-methoxyphenyl)-9-(oxan-4-yl)purine-2,8-diamine
Canonical SMILES	`COc1ccc(Nc2ncc3nc(Nc4ccccc4F)n(C4CCOCC4)c3n2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.93
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P45984	MAPK9	Homo sapiens	Human	PF00069	7.3	IC50	ChEMBL;BindingDB
P53779	MAPK10	Homo sapiens	Human	PF00069	7.2	IC50	ChEMBL;BindingDB
P45983	MAPK8	Homo sapiens	Human	PF00069	6.3	IC50	ChEMBL;BindingDB