ethyl 3-[2-[[(3R)-1-(cyclopropanecarbonyl)piperidin-3-yl]amino]pyrimidin-4-yl]-2-(3,4-dichlorophenyl)-5,6-dihydro-4H-cyclopenta[d]imidazole-5-carboxylate

InChIKey	`QWBLRTCRXZETHI-MUMRKEEXSA-N`
Compound Name	ethyl 3-[2-[[(3R)-1-(cyclopropanecarbonyl)piperidin-3-yl]amino]pyrimidin-4-yl]-2-(3,4-dichlorophenyl)-5,6-dihydro-4H-cyclopenta[d]imidazole-5-carboxylate
Canonical SMILES	`CCOC(=O)C1Cc2nc(-c3ccc(Cl)c(Cl)c3)n(-c3ccnc(N[C@@H]4CCCN(C(=O)C5CC5)C4)n3)c2C1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	5
Pfam Stratification	Homologous
Avg pChEMBL	7.67
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P53779	MAPK10	Homo sapiens	Human	PF00069	9.2	IC50	ChEMBL
P45984	MAPK9	Homo sapiens	Human	PF00069	8.1	IC50	ChEMBL
Q16539	MAPK14	Homo sapiens	Human	PF00069	7.3	IC50	ChEMBL
P45983	MAPK8	Homo sapiens	Human	PF00069	7.1	IC50	ChEMBL
P49841	GSK3B	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL