Molecule Details
InChIKeyQVWKRMXAYICTFS-UHFFFAOYSA-N
Compound NameN-benzyl-4-(1H-indazol-5-yl)thiazol-2-amine
Canonical SMILESc1ccc(CNc2nc(-c3ccc4[nH]ncc4c3)cs2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Homologous
Avg pChEMBL6.51
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
P51817 PRKX Homo sapiens Human PF00069 7.3 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.9 Ki ChEMBL;BindingDB
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.7 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.2 Ki ChEMBL;BindingDB
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.2 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.2 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 6.0 Ki ChEMBL