Molecule Details
InChIKeyQVRVXSZKCXFBTE-KPVNRNJOSA-N
Canonical SMILESCOc1cc2c(cc1OC)CN(CCCCNC(=O)c1cc(C)ccc1OCC[18F])CC2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.16
SourceChEMBL
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB14900
Drug NameISO-1 F-18
CAS Number945992-47-2
Groups investigational
ATC Codes nan
DescriptionISO-1 F-18 is under investigation in clinical trial NCT00968656 (Assessment of Cellular Proliferation in Tumors by Positron Emission Tomography (PET) Using [18F]ISO-1).

Cross-references: CHEMBL227072 ChemSpider: 20569206 ZINC: ZINC000101083658
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q5BJF2 TMEM97 Homo sapiens Human PF05241 8.7 Ki ChEMBL
Q99720 SIGMAR1 Homo sapiens Human PF04622 7.6 Ki ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q5BJF2 TMEM97 Sigma intracellular receptor 2 ligand targets