Molecule Details
InChIKeyQVNZBDLTUKCPGJ-SHQCIBLASA-N
Compound NameBms-561392
Canonical SMILESCc1cc(COc2ccc([C@]3(N)CCN([C@H](CC(C)C)C(=O)NO)C3=O)cc2)c2ccccc2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)10
Pfam Stratification Cross-Family
Avg pChEMBL6.71
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (10)
Target Gene Organism Category Pfam pChEMBL Type Source
P78536 ADAM17 Homo sapiens Human PF16698 PF00200 PF13574 9.7 IC50 ChEMBL;BindingDB
P08254 MMP3 Homo sapiens Human PF00045 PF00413 PF01471 6.5 IC50 ChEMBL
P22894 MMP8 Homo sapiens Human PF00045 PF00413 PF01471 6.5 IC50 ChEMBL
P14780 MMP9 Homo sapiens Human PF00040 PF00045 PF00413 6.4 IC50 ChEMBL
P03956 MMP1 Homo sapiens Human PF00045 PF00413 PF01471 6.4 IC50 ChEMBL
P45452 MMP13 Homo sapiens Human PF00045 PF00413 PF01471 6.3 IC50 ChEMBL
P09237 MMP7 Homo sapiens Human PF00413 PF01471 6.3 IC50 ChEMBL
O14672 ADAM10 Homo sapiens Human PF21299 PF00200 PF13574 6.3 IC50 ChEMBL
P08253 MMP2 Homo sapiens Human PF00040 PF00045 PF00413 6.3 IC50 ChEMBL
P50281 MMP14 Homo sapiens Human PF11857 PF00045 PF00413 PF01471 6.3 IC50 ChEMBL