Molecule Details
| InChIKey | QVMWSFYCPYOKBR-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-isopropyl-3-(naphthalen-1-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Canonical SMILES | CC(C)n1nc(-c2cccc3ccccc23)c2c(N)ncnc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.39 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9BJF5 | CDPK1 | Toxoplasma gondii | Pathogen | PF13499 PF00069 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q8MMZ7 | PKG | Toxoplasma gondii | Pathogen | PF00027 PF00069 | 6.5 | IC50 | BindingDB |
| A3FQ16 | Cryptosporidium parvum (strain Iowa II) | Pathogen | PF13499 PF00069 | 6.2 | IC50 | BindingDB |