Molecule Details
InChIKeyQTZUMCMRRPENJM-LJQANCHMSA-N
Compound NameN-[(1s)-1-(3-Chloro-4-Fluorophenyl)-2-Hydroxyethyl]-2-(Tetrahydro-2h-Pyran-4-Ylamino)-5,8-Dihydropyrido[3,4-D]pyrimidine-7(6h)-Carboxamide
Canonical SMILESO=C(N[C@H](CO)c1ccc(F)c(Cl)c1)N1CCc2cnc(NC3CCOCC3)nc2C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL8.05
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P28482 MAPK1 Homo sapiens Human PF00069 9.0 IC50 ChEMBL;BindingDB
P24941 CDK2 Homo sapiens Human PF00069 7.8 IC50 ChEMBL;BindingDB
P27361 MAPK3 Homo sapiens Human PF00069 7.3 IC50 ChEMBL