N,N'-Bis(4-{[(3r)-3-[(Biphenyl-4-Ylsulfonyl)(Propan-2-Yloxy)amino]-4-(Hydroxyamino)-4-Oxobutyl]amino}-4-Oxobutyl)benzene-1,3-Dicarboxamide

InChIKey	`QTGQZAQZBAEHLR-URZIEALYSA-N`
Compound Name	N,N'-Bis(4-{[(3r)-3-[(Biphenyl-4-Ylsulfonyl)(Propan-2-Yloxy)amino]-4-(Hydroxyamino)-4-Oxobutyl]amino}-4-Oxobutyl)benzene-1,3-Dicarboxamide
Canonical SMILES	`CC(C)ON([C@H](CCNC(=O)CCCNC(=O)c1cccc(C(=O)NCCCC(=O)NCC[C@H](C(=O)NO)N(OC(C)C)S(=O)(=O)c2ccc(-c3ccccc3)cc2)c1)C(=O)NO)S(=O)(=O)c1ccc(-c2ccccc2)cc1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	7.25
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P08253	MMP2	Homo sapiens	Human	PF00040 PF00045 PF00413	8.0	pIC50	TTD_MultiTarget
P14780	MMP9	Homo sapiens	Human	PF00040 PF00045 PF00413	7.8	IC50	ChEMBL;BindingDB
P50281	MMP14	Homo sapiens	Human	PF11857 PF00045 PF00413 PF01471	6.9	IC50	ChEMBL;BindingDB
Q9ULZ9	MMP17	Homo sapiens	Human	PF00045 PF00413 PF01471	6.9	pIC50	TTD_MultiTarget
P03956	MMP1	Homo sapiens	Human	PF00045 PF00413 PF01471	6.4	IC50	ChEMBL;BindingDB
P18843	nadE	Escherichia coli (strain K12)	Pathogen	PF02540	7.5	pIC50	TTD_MultiTarget