Molecule Details
| InChIKey | QTGPFGJUZIAJAF-KRWDZBQOSA-N |
|---|---|
| Compound Name | (R)-N-((4-(1,2-dihydroxyethyl)-1-(4-(pentafluoro-lambda6-sulfaneyl)phenyl)-1H-indazol-3-yl)methyl)acrylamide |
| Canonical SMILES | C=CC(=O)NCc1nn(-c2ccc(S(F)(F)(F)(F)F)cc2)c2cccc([C@@H](O)CO)c12 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.82 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15561 | TEAD4 | Homo sapiens | Human | PF01285 PF17725 | 7.3 | IC50 | BindingDB |
| P28347 | TEAD1 | Homo sapiens | Human | PF01285 PF17725 | 7.0 | IC50 | BindingDB |
| Q15562 | TEAD2 | Homo sapiens | Human | PF01285 PF17725 | 6.7 | IC50 | BindingDB |
| Q99594 | TEAD3 | Homo sapiens | Human | PF01285 PF17725 | 6.2 | IC50 | BindingDB |