Molecule Details
InChIKeyQSGKPYRFWJINEH-UHFFFAOYSA-N
Compound NameMethyl 9-(2,4-dichloroanilino)-[1,3]thiazolo[5,4-f]quinazoline-2-carboximidate
Canonical SMILESCOC(=N)c1nc2ccc3ncnc(Nc4ccc(Cl)cc4Cl)c3c2s1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Homologous
Avg pChEMBL7.74
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13627 DYRK1A Homo sapiens Human PF00069 9.7 IC50 ChEMBL;BindingDB
Q9Y463 DYRK1B Homo sapiens Human PF00069 9.6 IC50 ChEMBL;BindingDB
P49840 GSK3A Homo sapiens Human PF00069 8.1 IC50 ChEMBL;BindingDB
Q92630 DYRK2 Homo sapiens Human PF00069 8.0 IC50 ChEMBL;BindingDB
P06493 CDK1 Homo sapiens Human PF00069 7.6 IC50 ChEMBL;BindingDB
P49759 CLK1 Homo sapiens Human PF00069 7.6 IC50 ChEMBL;BindingDB
P11802 CDK4 Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
P24941 CDK2 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
P49760 CLK2 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
O43781 DYRK3 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
P49841 GSK3B Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB