4-amino-7-methyl-2-({5-methyl-1-[(3R)-oxolan-3-yl]-1H-pyrazol-4-yl}amino)-6-[(2R)-2-methylpyrrolidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile

InChIKey	`QSDVZPULRUJSBC-TZMCWYRMSA-N`
Compound Name	4-amino-7-methyl-2-({5-methyl-1-[(3R)-oxolan-3-yl]-1H-pyrazol-4-yl}amino)-6-[(2R)-2-methylpyrrolidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile
Canonical SMILES	`Cc1c(Nc2nc(N)c3c(C#N)c(N4CCC[C@H]4C)n(C)c3n2)cnn1[C@@H]1CCOC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.7
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q5S007	LRRK2	Homo sapiens	Human	PF23745 PF23744 PF23748 PF16095 PF25497 PF13855 PF00069 PF08477	7.7	IC50	ChEMBL;BindingDB
P36888	FLT3	Homo sapiens	Human	PF00047 PF07714	6.3	Kd	ChEMBL;BindingDB
Q9UBF8	PI4KB	Homo sapiens	Human	PF00454 PF21245	6.1	Kd	ChEMBL;BindingDB