InChIKey	QRXWMOHMRWLFEY-UHFFFAOYSA-N
Canonical SMILES	NNC(=O)c1ccncc1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Cross-Family
Avg pChEMBL	8.73
Source	ChEMBL;BindingDB

DrugBank ID	DB00951
Drug Name	Isoniazid
CAS Number	54-85-3
Groups	approved investigational
ATC Codes	J04AM04 J04AM01 J04AM03 J04AM02 J04AM09 J04AM06 J04AC01 J04AM05 J04AM07 J04AM08 J04AM12 J04AC51
Description	Antibacterial agent used primarily as a tuberculostatic. It remains the treatment of choice for tuberculosis.

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Categories: Agents Causing Muscle Toxicity Agents that reduce seizure threshold Anti-Bacterial Agents Anti-Infective Agents Antiinfectives for Systemic Use Antimycobacterials Cytochrome P-450 CYP1A2 Inhibitors Cytochrome P-450 CYP1A2 Inhibitors (strength unknown) Cytochrome P-450 CYP2A6 Inhibitors Cytochrome P-450 CYP2A6 Inhibitors (strength unknown) Cytochrome P-450 CYP2C19 Inhibitors Cytochrome P-450 CYP2C19 Inhibitors (strong) Cytochrome P-450 CYP2C19 Inhibitors (weak) Cytochrome P-450 CYP2C8 Inhibitors Cytochrome P-450 CYP2C8 Inhibitors (strength unknown) Cytochrome P-450 CYP2C9 Inhibitors Cytochrome P-450 CYP2C9 Inhibitors (strength unknown) Cytochrome P-450 CYP2D6 Inhibitors Cytochrome P-450 CYP2D6 Inhibitors (weak) Cytochrome P-450 CYP2E1 Inducers Cytochrome P-450 CYP2E1 Inducers (strength unknown) Cytochrome P-450 CYP2E1 Inhibitors Cytochrome P-450 CYP2E1 Inhibitors (moderate) Cytochrome P-450 CYP2E1 Substrates Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Inhibitors (moderate) Cytochrome P-450 CYP3A4 Inhibitors (strength unknown) Cytochrome P-450 Enzyme Inducers Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Drugs for Treatment of Tuberculosis Drugs that are Mainly Renally Excreted Fatty Acid Synthesis Inhibitors Hepatotoxic Agents Hydrazides Hydrazines Hyperglycemia-Associated Agents Hypolipidemic Agents Isonicotinic Acids Pyridines Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome

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Cross-references: BindingDB: 50336507 ChEBI: 6030 CHEMBL64 ChemSpider: 3635 Drugs Product Database (DPD): 6618 C07054 D00346 PDB: NIZ PharmGKB: PA450112 PubChem:3767 PubChem:46506039 RxCUI: 6038 Therapeutic Targets Database: DAP000011 Wikipedia: Isoniazid ZINC: ZINC000000001590