Molecule Details
| InChIKey | QPFCZCMRUOQZRG-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2,4-dihydroxy-N-[4-[3-methyl-5-(thiophen-2-ylmethylsulfamoyl)-2-pyridinyl]phenyl]-N-(pyridin-3-ylmethyl)benzamide |
| Canonical SMILES | Cc1cc(S(=O)(=O)NCc2cccs2)cnc1-c1ccc(N(Cc2cccnc2)C(=O)c2ccc(O)cc2O)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.25 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15118 | PDK1 | Homo sapiens | Human | PF10436 PF02518 | 7.0 | IC50 | ChEMBL |
| Q15119 | PDK2 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |
| Q15120 | PDK3 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |
| Q16654 | PDK4 | Homo sapiens | Human | PF10436 PF02518 | 6.0 | IC50 | ChEMBL |