7-[5,5,5-trifluoro-4-hydroxy-4-(1H-indol-2-ylmethyl)-2-methylpentan-2-yl]-2,3-dihydro-1-benzofuran-5-carbonitrile

InChIKey	`QOZZBCZFOZCNQK-UHFFFAOYSA-N`
Compound Name	7-[5,5,5-trifluoro-4-hydroxy-4-(1H-indol-2-ylmethyl)-2-methylpentan-2-yl]-2,3-dihydro-1-benzofuran-5-carbonitrile
Canonical SMILES	`CC(C)(CC(O)(Cc1cc2ccccc2[nH]1)C(F)(F)F)c1cc(C#N)cc2c1OCC2`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	6.65
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P04150	NR3C1	Homo sapiens	Human	PF02155 PF00104 PF00105	7.4	IC50	ChEMBL;BindingDB
P08235	NR3C2	Homo sapiens	Human	PF00104 PF00105	6.4	IC50	ChEMBL;BindingDB
P06401	PGR	Homo sapiens	Human	PF00104 PF02161 PF00105	6.2	IC50	ChEMBL;BindingDB