Molecule Details
InChIKeyQOECJCJVIMVJGX-UHFFFAOYSA-N
Compound Name2-Cyclohexyl-6-methoxy-N-(1-(1-methylethyl)-4-piperidinyl)-7-(3-(1-pyrrolidinyl)propoxy)-4-quinazolinamine
Canonical SMILESCOc1cc2c(NC3CCN(C(C)C)CC3)nc(C3CCCCC3)nc2cc1OCCCN1CCCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.69
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9H9B1 EHMT1 Homo sapiens Human PF12796 PF13637 PF21533 PF05033 PF00856 7.7 IC50 ChEMBL;BindingDB
Q96KQ7 EHMT2 Homo sapiens Human PF00023 PF12796 PF21533 PF05033 PF00856 7.3 IC50 ChEMBL;BindingDB
O60341 KDM1A Homo sapiens Human PF01593 PF04433 6.8 IC50 ChEMBL
P11229 CHRM1 Homo sapiens Human PF00001 6.4 Ki ChEMBL
P18825 ADRA2C Homo sapiens Human PF00001 6.4 Ki ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 6.3 Ki ChEMBL
P08172 CHRM2 Homo sapiens Human PF00001 6.3 Ki ChEMBL
P08173 CHRM4 Homo sapiens Human PF00001 6.3 Ki ChEMBL