Molecule Details
| InChIKey | QNOOVTZVMOOSAW-FQEVSTJZSA-N |
|---|---|
| Compound Name | US9073917, 12-comparative |
| Canonical SMILES | CCOC(=O)c1[nH]cc2c1NC1=C(C(=O)CCC1)[C@@H]2c1ccc(Sc2nc3ccccc3[nH]2)o1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.15 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q96GD4 | AURKB | Homo sapiens | Human | PF00069 | 8.5 | IC50 | ChEMBL;BindingDB |
| Q9NQS7 | INCENP | Homo sapiens | Human | PF03941 PF12178 | 8.5 | IC50 | ChEMBL |
| O14965 | AURKA | Homo sapiens | Human | PF00069 | 8.4 | IC50 | ChEMBL;BindingDB |
| Q14432 | PDE3A | Homo sapiens | Human | PF00233 | 7.2 | IC50 | ChEMBL;BindingDB |