Molecule Details
InChIKeyQMGVPVSNSZLJIA-FVWCLLPLSA-N
Compound NameStrychnine
Canonical SMILESO=C1C[C@@H]2OCC=C3CN4CC[C@]56c7ccccc7N1[C@H]5[C@H]2[C@H]3C[C@H]46
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.83
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB15954
Drug NameStrychnine
CAS Number57-24-9
Groups experimental
ATC Codes nan
Descriptionnan

Categories: Alkaloids Central Nervous System Agents Central Nervous System Stimulants Compounds used in a research, industrial, or household setting Convulsants Glycine Agents Heterocyclic Compounds, Fused-Ring Indole Alkaloids Indoles Indolizidines Indolizines Neurotransmitter Agents Noxae Poisons Secologanin Tryptamine Alkaloids Toxic Actions
Cross-references: BindingDB: 50225707 ChEBI: 28973 CHEMBL227934 ChemSpider: 389877 C06522 PDB: SY9 RxCUI: 66422 Wikipedia: Strychnine ZINC: ZINC000000119434
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P23415 GLRA1 Homo sapiens Human PF02931 PF02932 6.9 IC50 ChEMBL;BindingDB
P48167 GLRB Homo sapiens Human PF02931 PF02932 6.7 IC50 ChEMBL
DrugBank Target Actions (4)
Target Gene Target Name Action Type
O75311 O75311 Glycine receptor subunit alpha-3 antagonist targets
P23415 GLRA1 Glycine receptor subunit alpha-1 antagonist targets
P23416 P23416 Glycine receptor subunit alpha-2 antagonist targets
P48167 GLRB Glycine receptor subunit beta antagonist targets