Molecule Details
| InChIKey | QMBIGGCLOHYBHN-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[2-(3-fluoro-6-methoxy-1,5-naphthyridin-4-yl)ethyl]-N-[(4-methylphenyl)methyl]piperidin-4-amine |
| Canonical SMILES | COc1ccc2ncc(F)c(CCN3CCC(NCc4ccc(C)cc4)CC3)c2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.28 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P0A0K8 | gyrB | Staphylococcus aureus | Pathogen | PF00204 PF00986 PF02518 PF01751 | 8.4 | IC50 | ChEMBL |
| P20831 | gyrA | Staphylococcus aureus | Pathogen | PF03989 PF00521 | 8.4 | IC50 | ChEMBL |
| P0C1S7 | parE | Staphylococcus aureus | Pathogen | PF00204 PF00986 PF02518 PF01751 | 6.2 | IC50 | ChEMBL |
| P0C1U9 | parC | Staphylococcus aureus | Pathogen | PF03989 PF00521 | 6.2 | IC50 | ChEMBL |