Molecule Details
InChIKeyQLUYMIVVAYRECT-OCCSQVGLSA-N
Compound Name2-(2-chlorophenyl)-5,7-dihydroxy-8-((2R,3S)-2-(hydroxymethyl)-1-methylpyrrolidin-3-yl)chromen-4-one
Canonical SMILESCN1CC[C@@H](c2c(O)cc(O)c3c(=O)cc(-c4ccccc4Cl)oc23)[C@@H]1CO
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Cross-Family
Avg pChEMBL7.28
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q86XP3 DDX42 Homo sapiens Human PF00270 PF00271 8.7 Kd ChEMBL
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 7.7 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 7.7 IC50 ChEMBL
P53350 PLK1 Homo sapiens Human PF00069 PF00659 7.7 Kd ChEMBL
O76039 CDKL5 Homo sapiens Human PF00069 7.6 Kd ChEMBL
P11802 CDK4 Homo sapiens Human PF00069 7.2 IC50 ChEMBL;BindingDB
P24385 CCND1 Homo sapiens Human PF02984 PF00134 7.2 IC50 ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
P14635 CCNB1 Homo sapiens Human PF02984 PF00134 7.1 IC50 ChEMBL
P20248 CCNA2 Homo sapiens Human PF02984 PF00134 PF16500 6.7 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.7 IC50 ChEMBL;BindingDB
Q9UPZ9 CILK1 Homo sapiens Human PF00069 6.0 Kd ChEMBL