(1R,2R,3S,4R,5S)-4-[2-chloro-6-[(3-fluorophenyl)methylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide

InChIKey	`QLKCAKIBINXIIQ-KZOVSVDNSA-N`
Compound Name	(1R,2R,3S,4R,5S)-4-[2-chloro-6-[(3-fluorophenyl)methylamino]purin-9-yl]-2,3-dihydroxy-N-methylbicyclo[3.1.0]hexane-1-carboxamide
Canonical SMILES	`CNC(=O)[C@]12C[C@@H]1[C@@H](n1cnc3c(NCc4cccc(F)c4)nc(Cl)nc31)[C@H](O)[C@@H]2O`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.4
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P0DMS8	ADORA3	Homo sapiens	Human	PF00001	8.6	Ki	ChEMBL
P30542	ADORA1	Homo sapiens	Human	PF00001	6.2	Ki	ChEMBL