Molecule Details
| InChIKey | QKYONSSKLFQUAK-UHFFFAOYSA-N |
|---|---|
| Compound Name | 9-ethyl-6,6-dimethyl-11-oxo-8-(2H-triazol-4-yl)-5H-benzo[b]carbazole-3-carbonitrile |
| Canonical SMILES | CCc1cc2c(cc1-c1cnn[nH]1)C(C)(C)c1[nH]c3cc(C#N)ccc3c1C2=O |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.66 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q96SB4 | SRPK1 | Homo sapiens | Human | PF00069 | 9.1 | IC50 | ChEMBL;BindingDB |
| P78362 | SRPK2 | Homo sapiens | Human | PF00069 | 8.1 | IC50 | ChEMBL;BindingDB |
| Q9UM73 | ALK | Homo sapiens | Human | PF12810 PF00629 PF07714 | 6.7 | IC50 | ChEMBL;BindingDB |
| Q9HC35 | EML4 | Homo sapiens | Human | PF23409 PF23414 PF03451 | 6.7 | IC50 | ChEMBL |